Diagnostic value of changes in matrix metalloproteinases upon pancreatic diseases
نویسندگان
چکیده
منابع مشابه
Degradomics of matrix metalloproteinases in inflammatory diseases.
Organisms have evolved to react to stress, tissue damage and pathogen invasion to assure their survival. Leukocytes are the primary responders and they regulate repair, immune defense and inflammation with the aid of a wide variety of other cells (e.g. epithelial, fibroblasts). To assure proper responses, a plethora of proteins are involved including signaling molecules, chemokines and protease...
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Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have been increasingly linked to both normal physiology and abnormal pathology in the kidney. Collectively able to degrade all components of the extracellular matrix, MMPs were originally thought to antagonize the development of fibrotic diseases solely through digestion of excessive matrix. However, increasing ...
متن کاملP 88: Matrix Metalloproteinases in Neuroinflammation
Matrix metalloproteinases (MMPs) are a family of neutral proteinases that are important in normal development, cellular differentiation or migration, angiogenesis, neurogenesis, wound repair, and a wide range of pathological processes such as oxidative stress and neuroinflammation. MMPs have been demonstrated to increase the permeability of the blood–brain barrier (BBB) by degrading the c...
متن کاملMatrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis.
AIM To identify the diagnostic accuracy of gingival crevicular fluid (GCF) candidate biomarkers to discriminate periodontitis from the inflamed and healthy sites, and to compare the performance of two independent matrix metalloproteinase (MMP)-8 immunoassays. MATERIALS AND METHODS Cross sectional study. GCF (N = 58 sites) was collected from healthy, gingivitis and chronic periodontitis volunt...
متن کاملOsteoarticular complications of brucellosis: The diagnostic value and importance of detection matrix metalloproteinases.
OBJECTIVES Matrix metalloproteinases (MMPs) has been implicated in the pathogenesis of infective, cancer and autoimmune diseases. In this study, we investigated the serum level of MMPs and its clinical importance in human brucellosis. PATIENTS AND METHODS This study included 60 brucellosis patients treated at the Clinic for Infectious Diseases, Clinical Centre, University of Sarajevo. Matrix ...
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ژورنال
عنوان ژورنال: Bulletin of the Club of Pancreatologists
سال: 2017
ISSN: 2077-5067
DOI: 10.33149/vkp.2017.03.06